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KMID : 1149020170190010015
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Journal of Korean Society of Computed Tomographic Technology
2017 Volume.19 No. 1 p.15 ~ p.24
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A Comparative Study on the Differences of Fat CT Number at Nonenhanced phase and Arterial phase of Liver Volumetry CT using Dual Energy
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Kim Se-Hwan
Lee Ki-Baek
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Abstract
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Purpose : It is important to measure the amount of fat in liver parenchyma which hinders function of the liver in order to evaluate liver function of liver donor. The purpose of this study was to evaluate the usability of 3-material decomposition by comparing measured fat values between non-enhanced phase and arterial phase in dual-energy Computed Tomography (DECT).
Materials and Methods : Between February, 2015 and April , 2016, 29 liver donors who underwent DECT for liver transplantation enrolled in this study. Non-contrast phase and arterial phase were performed on a fast kilovoltage-switching DECT scanner (Discovery 750HD scanner, GE Healthcare, Milwaukee, Wis, USA) and thin data of Gemstone Spectral Imaging (GSI) was obtained with the GSI-44 protocol: Large, 0.7 s, 40 mm, 275 mA, 10.68 mGy, and GSI assist off. Fat images were acquired by using 3-material decomposition (fat-water-iodine) on workstation. In 3 consecutive images which show the largest boundary of the liver, The values of Hounsfield Unit(HU) and Standard Deviation(SD) about fat were measured on the same Region of Interest (ROI): segment 5 or segment 8 of liver parenchyma.
Results : The differences of HU Values on fat between non-enhanced phase and arterial phase in axial was average 0.49 (range: 0 to 2), coronal was average 0.51(range : 0.03 to 1.63), sagittal was average 0.44(range : 0 to 1.97). Total difference was 0.48 (range : 0 to 2). The differences of SD on fat between non-enhanced phase and arterial phase in axial was average 0.48(range: 0 to 1.97), coronal was average 0.61(range: 0.07 to 1.33), sagittal was 0.45(range: 0 to 1.37). That differences were not statistically significant (p>0.05).
Conclusion : There were no big differences of measured fat amount between non-contrast and arterial phasic 3-material decomposition imaging. It was enough to quantify fat only with arterial phasic 3-material decomposition imaging. When performing liver volumetry CT for liver fat measurement in liver donor before liver transplantation, we can reduce radiation dose by skipping non-contrast phase.
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KEYWORD
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Dual-energy CT, Liver transplantation, Liver fat quantification, Material demcomposition
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